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Treatment with insulin and oral medications for people with diabetes (U.

For type 1 diabetes, a large study asking if small doses of insulin could prevent type 1 diabetes in high-risk individuals showed this strategy did not work.

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Three-year mortality in diabetic patients treated with different combinations of insulin secretagogues and metformin".

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All NICE clinical guidelines are prepared in relation to the National Health Service in England and Wales.

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Metformin produced more gastrointestinal symptoms (range, 2% to 63%) than most other oral diabetes agents (range, 0% to 36% for thiazolidinediones, 0% to 32% for second-generation sulfonylureas, and 8% to 11% for repaglinide).

American Association of Clinical Endocrinologists Statement on the Use of A1C for the Diagnosis of Diabetes.

When women reach menopause, estrogen levels decline in the bloodstream.

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The method of claim 9, comprising administering a dose with breakfast, or the first meal of the day; administering a dose with the last, or evening meal, and wherein the subject also consumes a third meal or midday meal.

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Barring a laboratory error, such patients will likely have test results near the margins of the diagnostic threshold.

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There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with repaglinide or any other anti-diabetic drug.

Drinking alcoholic beverages, especially binge drinking, can cause hypoglycemia.

Sulfonylureas can cause hemolytic anemia in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency.

Repaglinide is an oral blood glucose-lowering drug of the meglitinide class used in the management of type 2 diabetes mellitus (also known as non-insulin dependent diabetes mellitus or NIDDM).

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Although they are not clearly superior to newer agents, sulfonylureas remain a reasonable alternative as second-line therapy, especially if cost is an issue.

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The onset of action for this class is reported as initial response and peak response after medication administration.

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Effect of an intensive exercise intervention strategy on modifiable cardiovascular risk factors in subjects with type 2 diabetes mellitus: a randomized controlled trial: the Italian Diabetes and Exercise Study (IDES).

The Task Force recommends that all patients with diabetes treated with insulin at home be treated with a scheduled subcutaneous (sc) insulin regimen in the hospital.

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Insulin secretagogues should be used with caution in the hospital, since food intake may be interrupted by diagnostic tests and procedures.

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